Anti-inflammatory Activity and Mechanism of Action of Vitex negundo Linn
نویسندگان
چکیده
منابع مشابه
Anti-inflammatory Activity of Extracts and Compounds from Vitex Negundo
RASADAH, M. A., FAREDIAH, A., WONG, C. L. & ONG, B. K. 2005. Antiinflammatory activity of extracts and compounds from Vitex negundo. The antiinflammatory activity of the leaf extract of Vitex negundo was investigated on topical administration using the TPA (tetradecanoylphorbol acetate)-induced mouse ear inflammation model. The crude methanolic extract of V. negundo showed moderate inhibition (...
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Chemical investigation of Vitex negundo seeds afforded four new lignans, including a phenylindene-type lignan, vitexdoin F (1), and three phenylnaphthalene-type lignans, vitexdoins G, H and I (2-4). Their structures were elucidated by detailed spectroscopic analyses on the basis of NMR, IR, and MS data. All compounds were evaluated for their anti-inflammatory and anti-osteoporotic activities, e...
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Tail flick test in rats and acetic acid induced writhing in mice were employed to study the antinociceptive activity of ethanolic leaf extract of Vitex-negundo (VN) (100, 250 and 500 mg/kg, p.o). The effect was compared with meperidine (40 mg/kg, sc) in tail flick method and aspirin (50 mg/kg, p.o) in writhing test as a standard control respectively. An interaction with naloxone hydrochloride w...
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BACKGROUND & OBJECTIVES Currently, herbal preparations are clinically used as functional food, food supplements or as add on therapy, which affects the bioavailability and also the net therapeutic potential of co-administered allopathic drugs. Therefore, it is important to assess the interaction among these two classes of drugs. Here we studied the interaction between orally-administered ethano...
متن کاملAnti- Inflammatory Activity of Vitex Trifolia Linn. (verbaneaceae) Leaves Extracts
Objectives: The present study was carried out to evaluate the antiinflammatory effect of extracts of leaves of Vitex trifolia Linn. (Verbaneaceae). Methods: The anti inflammatory activity of plant extracts at different dose intervals was evaluated by using two models Carrageenan induced rat paw edema and Xylene induced ear edema in Mice. Acute inflammation in rats was induced by injecting Carra...
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ژورنال
عنوان ژورنال: International Journal of Pharmacology
سال: 2006
ISSN: 1811-7775
DOI: 10.3923/ijp.2006.303.308